Personality Disorders
Borderline Personality Disorder
ICD-10-CM: F60.3
1. Criteria
DSM Criteria
Criterion A
- A pervasive pattern of instability in interpersonal relationships, self-image, and affects, with marked impulsivity, begins by early adulthood and is present across contexts.
DSM Criteria
Criterion B
- At least 5 of the following are present: frantic efforts to avoid abandonment, unstable intense relationships, identity disturbance, impulsivity in potentially self-damaging areas, recurrent suicidal behavior or self-injury, affective instability, chronic emptiness, intense anger, or transient stress-related paranoia or dissociation.
2. Context
- Borderline personality disorder is usually experienced as instability that touches nearly everything: relationships, identity, mood, anger, impulsivity, and the ability to feel steady from one moment to the next. The pattern is broad, longstanding, and often most visible under interpersonal stress.
- Pattern across settings: The diagnosis is about a pervasive pattern, not a single crisis, breakup, or emotionally intense week.
- Risk assessment: Self-harm, suicidality, dissociation, substance use, and impulsive behavior need repeated and careful assessment over time.
- Medication limits: Medication may help with pieces of the picture, but psychotherapy remains the center of treatment for the disorder itself.
- Clinical focus: Brief screening instrument for borderline personality features.
3. Validated scales
MSI-BPD
Brief screening instrument for borderline personality features.
ZAN-BPD
Clinician-rated severity measure for borderline symptom domains.
4. FDA approved treatments
Diagnosis-specific FDA indications
This prototype does not list a core borderline-personality-disorder-specific FDA medication indication; medication use is generally symptom- or comorbidity-targeted. Verify current labeling for any off-label strategy.
No diagnosis-specific FDA medication entry is listed in this prototype section.
Common off-label medications
Interventional psychiatry modalities
- Interventional psychiatry is not standard for borderline personality disorder itself.
- ECT may be used for severe comorbid mood syndromes, not for core BPD.
- TMS and ketamine are being explored mainly for comorbid affective symptoms.
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5. Top management articles
- Management review for Borderline Personality Disorder PubMed search
- Borderline Personality Disorder treatment guideline PubMed search
- Borderline Personality Disorder pharmacotherapy or psychotherapy review PubMed search