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Treatments and Medications

Narcolepsy Treatments and Medications

This page summarizes the main treatment lanes attached to Narcolepsy and links back to the full diagnosis profile.

Main diagnosis page

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FDA-approved medications for excessive daytime sleepiness in narcolepsy

  • Several wake-promoting agents and alerting medications carry narcolepsy labeling, though product-specific indications and age ranges differ.
  • Medications: Modafinil, Armodafinil, Solriamfetol, Pitolisant

FDA-approved medications for cataplexy or mixed narcolepsy symptoms

  • Oxybate products are important FDA-approved options when cataplexy or severe daytime sleepiness is part of the narcolepsy picture.
  • Medications: Sodium oxybate, Low-sodium oxybate

Common off-label medications

  • Methylphenidate
  • Amphetamine formulations
  • Venlafaxine for cataplexy

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